Articles
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Plant Biology & Bioregenerative Systems
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Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis
Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis
Plant Biology & Bioregenerative Systems
Abstractive Summary
Study examining investigation of simulated microgravity effects on streptococcus mutans. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining investigation of simulated microgravity effects on streptococcus mutans. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
investigation, simulated, microgravity, effects, streptococcus, mutans, physiology, global, gene, expression, genes, expression, study, examining, investigation, simulated, microgravity, effects, streptococcus, mutans, changes, long, study, examining, investigation, simulated, microgravity, effects, streptococcus, mutans
Abstractive Keywords
changes, long, study, examining, investigation, simulated, microgravity, effects, streptococcus, mutans
Extractive Keywords
genes, expression, study, examining, investigation, simulated, microgravity, effects, streptococcus, mutans
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