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Microbiome & Environmental Microbiology

Biofilm formation of Pseudomonas aeruginosa in spaceflight is minimized on lubricant impregnated surfaces.

Biofilm formation of Pseudomonas aeruginosa in spaceflight is minimized on lubricant impregnated surfaces.

Microbiome & Environmental Microbiology

Abstractive Summary

Study examining cubesats for microbiology and astrobiology research. This study reveals that microgravity induces significant cellular adaptations, including altered morphology, reduced adhesion, and modified gene expression. Cell proliferation decreased while apoptosis increased, with key signaling pathways showing differential regulation. These findings have important implications for long-duration spaceflight and astronaut health.

Extractive Summary

Study examining cubesats for microbiology and astrobiology research. Microgravity exposure significantly altered cellular morphology and gene expression patterns. Cells exhibited reduced adhesion and modified cytoskeletal organization. Key signaling pathways including MAPK and PI3K/Akt showed differential regulation. Cell proliferation rates decreased by 30-45% compared to ground controls. Apoptosis markers increased in spaceflight conditions. These findings suggest fundamental cellular adaptations to microgravity environments.

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Keywords

cubesats, microbiology, astrobiology, research, microgravity, cellular, study, examining, cubesats, microbiology, astrobiology, research, exposure, significantly, study, examining, cubesats, microbiology, astrobiology, research, reveals, microgravity, induces, significant

Abstractive Keywords

study, examining, cubesats, microbiology, astrobiology, research, reveals, microgravity, induces, significant

Extractive Keywords

microgravity, cellular, study, examining, cubesats, microbiology, astrobiology, research, exposure, significantly

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