Articles

Plant Biology & Bioregenerative Systems

Caenorhabditis elegans in microgravity: An omics perspective

Caenorhabditis elegans in microgravity: An omics perspective

Plant Biology & Bioregenerative Systems

Abstractive Summary

Study examining enabling clonal analyses of yeast in outer space. Exposure to cosmic radiation causes substantial DNA damage and oxidative stress, with repair mechanisms partially effective. Cell cycle checkpoints and apoptosis are activated, but long-term cancer risk remains elevated at 3-5% for Mars missions. Effective radiation countermeasures are critical for deep space exploration.

Extractive Summary

Study examining enabling clonal analyses of yeast in outer space. Cosmic radiation exposure caused significant DNA damage with increased double-strand breaks. Cellular repair mechanisms were partially effective but overwhelmed at higher doses. Oxidative stress markers were elevated substantially. Cell cycle checkpoints showed prolonged activation. Apoptosis rates increased dose-dependently. Long-term cancer risk estimates ranged from 3-5% for Mars missions.

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Keywords

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Abstractive Keywords

space, radiation, effective, study, examining, enabling, clonal, analyses, yeast, outer

Extractive Keywords

increased, study, examining, enabling, clonal, analyses, yeast, outer, space, cosmic

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