Articles
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Metabolism & Nutrition
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Draft Genome Sequences of Aspergillus and Penicillium Species Isolated from the International Space Station and Crew Resupply Vehicle Capsule
Draft Genome Sequences of Aspergillus and Penicillium Species Isolated from the International Space Station and Crew Resupply Vehicle Capsule
Metabolism & Nutrition
Abstractive Summary
Study examining assessing the risk of transfer of microorganisms at. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining assessing the risk of transfer of microorganisms at. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
assessing, risk, transfer, microorganisms, international, space, station, cargo, delivery, commercial, genes, expression, study, examining, assessing, risk, transfer, microorganisms, genome, wide, changes, long, study, examining, assessing, risk, transfer, microorganisms, spaceflight, triggers
Abstractive Keywords
changes, long, study, examining, assessing, risk, transfer, microorganisms, spaceflight, triggers
Extractive Keywords
genes, expression, study, examining, assessing, risk, transfer, microorganisms, genome, wide
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