Articles
●
Cardiovascular & Fluid Dynamics
●
Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart
Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart
Cardiovascular & Fluid Dynamics
Abstractive Summary
Study examining effects of low-dose rate ϳ-irradiation combined with simulated. Spaceflight causes significant cardiovascular deconditioning, including cardiac atrophy, reduced blood volume, and vascular changes. Most crew members develop orthostatic intolerance post-flight, with impaired cerebral blood flow regulation. Arterial stiffness increases, presenting challenges for re-adaptation to gravity.
Extractive Summary
Study examining effects of low-dose rate ϳ-irradiation combined with simulated. Cardiovascular deconditioning was observed with reduced cardiac mass and altered vascular function. Blood volume decreased by 10-15% within first weeks. Orthostatic intolerance developed in 70% of crew post-flight. Carotid artery stiffness increased during flight. Cardiac atrophy affected left ventricular mass. Cerebral blood flow regulation was impaired upon return to gravity.
283
Keywords
effects, dose, rate, irradiation, combined, simulated, microgravity, markers, oxidative, stress, cardiac, mass, blood, flight, study, examining, effects, dose, rate, irradiation, blood, study, examining, effects, dose, rate, irradiation, combined, simulated, spaceflight
Abstractive Keywords
blood, study, examining, effects, dose, rate, irradiation, combined, simulated, spaceflight
Extractive Keywords
cardiac, mass, blood, flight, study, examining, effects, dose, rate, irradiation
Topic Match Articles