Articles
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Plant Biology & Bioregenerative Systems
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Functional changes in the snail statocyst system elicited by microgravity
Functional changes in the snail statocyst system elicited by microgravity
Plant Biology & Bioregenerative Systems
Abstractive Summary
Study examining rnaseq analysis of rodent spaceflight experiments is confounded. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining rnaseq analysis of rodent spaceflight experiments is confounded. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
rnaseq, analysis, rodent, spaceflight, experiments, confounded, sample, collection, techniques, genes, analysis, expression, study, examining, rnaseq, rodent, spaceflight, experiments, confounded, spaceflight, changes, long, study, examining, rnaseq, analysis, rodent, experiments, confounded
Abstractive Keywords
spaceflight, changes, long, study, examining, rnaseq, analysis, rodent, experiments, confounded
Extractive Keywords
genes, analysis, expression, study, examining, rnaseq, rodent, spaceflight, experiments, confounded
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