Articles
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Cardiovascular & Fluid Dynamics
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Functional consequences of radiation-induced oxidative stress in cultured neural stem cells and the brain exposed to charged particle irradiation
Functional consequences of radiation-induced oxidative stress in cultured neural stem cells and the brain exposed to charged particle irradiation
Cardiovascular & Fluid Dynamics
Abstractive Summary
Study examining functional consequences of radiation-induced oxidative stress in cultured. Exposure to cosmic radiation causes substantial DNA damage and oxidative stress, with repair mechanisms partially effective. Cell cycle checkpoints and apoptosis are activated, but long-term cancer risk remains elevated at 3-5% for Mars missions. Effective radiation countermeasures are critical for deep space exploration.
Extractive Summary
Study examining functional consequences of radiation-induced oxidative stress in cultured. Cosmic radiation exposure caused significant DNA damage with increased double-strand breaks. Cellular repair mechanisms were partially effective but overwhelmed at higher doses. Oxidative stress markers were elevated substantially. Cell cycle checkpoints showed prolonged activation. Apoptosis rates increased dose-dependently. Long-term cancer risk estimates ranged from 3-5% for Mars missions.
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Keywords
functional, consequences, radiation, induced, oxidative, stress, cultured, neural, stem, cells, radiation, oxidative, stress, increased, study, examining, functional, consequences, induced, cultured, radiation, oxidative, stress, effective, study, examining, functional, consequences, induced, cultured
Abstractive Keywords
radiation, oxidative, stress, effective, study, examining, functional, consequences, induced, cultured
Extractive Keywords
radiation, oxidative, stress, increased, study, examining, functional, consequences, induced, cultured
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