Articles
●
Cardiovascular & Fluid Dynamics
●
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight
Cardiovascular & Fluid Dynamics
Abstractive Summary
Study examining genome and clonal hematopoiesis stability contrasts with immune,. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Extractive Summary
Study examining genome and clonal hematopoiesis stability contrasts with immune,. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.
295
Keywords
genome, clonal, hematopoiesis, stability, contrasts, immune, cfdna, mitochondrial, telomere, length, immune, cell, study, examining, genome, clonal, hematopoiesis, stability, contrasts, spaceflight, immune, function, cell, study, examining, genome, clonal, hematopoiesis, stability, contrasts
Abstractive Keywords
immune, function, cell, study, examining, genome, clonal, hematopoiesis, stability, contrasts
Extractive Keywords
immune, cell, study, examining, genome, clonal, hematopoiesis, stability, contrasts, spaceflight
Topic Match Articles