Articles
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Microbiome & Environmental Microbiology
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In situ monitoring of barrier function on-chip via automated, non-invasive luminescence sensing.
In situ monitoring of barrier function on-chip via automated, non-invasive luminescence sensing.
Microbiome & Environmental Microbiology
Abstractive Summary
Study examining spatial characterization of microbial communities on multi-species leafy. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining spatial characterization of microbial communities on multi-species leafy. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
spatial, characterization, microbial, communities, multi, species, leafy, greens, grown, simultaneously, genes, expression, study, examining, spatial, characterization, microbial, communities, multi, species, changes, long, study, examining, spatial, characterization, microbial, communities, multi, species
Abstractive Keywords
changes, long, study, examining, spatial, characterization, microbial, communities, multi, species
Extractive Keywords
genes, expression, study, examining, spatial, characterization, microbial, communities, multi, species
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