Articles
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Gene Expression & Molecular Biology
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Induction of attachment-independent biofilm formation and repression of Hfq expression by low-fluid-shear culture of Staphylococcus aureus
Induction of attachment-independent biofilm formation and repression of Hfq expression by low-fluid-shear culture of Staphylococcus aureus
Gene Expression & Molecular Biology
Abstractive Summary
Study examining induction of attachment-independent biofilm formation and repression of. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining induction of attachment-independent biofilm formation and repression of. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
induction, attachment, independent, biofilm, formation, repression, expression, fluid, shear, culture, genes, expression, study, examining, induction, attachment, independent, biofilm, formation, repression, changes, long, study, examining, induction, attachment, independent, biofilm, formation, repression
Abstractive Keywords
changes, long, study, examining, induction, attachment, independent, biofilm, formation, repression
Extractive Keywords
genes, expression, study, examining, induction, attachment, independent, biofilm, formation, repression
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