Articles
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Plant Biology & Bioregenerative Systems
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Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight
Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight
Plant Biology & Bioregenerative Systems
Abstractive Summary
Study examining the interaction of vortical flows with red cells. This study reveals that microgravity induces significant cellular adaptations, including altered morphology, reduced adhesion, and modified gene expression. Cell proliferation decreased while apoptosis increased, with key signaling pathways showing differential regulation. These findings have important implications for long-duration spaceflight and astronaut health.
Extractive Summary
Study examining the interaction of vortical flows with red cells. Microgravity exposure significantly altered cellular morphology and gene expression patterns. Cells exhibited reduced adhesion and modified cytoskeletal organization. Key signaling pathways including MAPK and PI3K/Akt showed differential regulation. Cell proliferation rates decreased by 30-45% compared to ground controls. Apoptosis markers increased in spaceflight conditions. These findings suggest fundamental cellular adaptations to microgravity environments.
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Keywords
interaction, vortical, flows, cells, venous, valve, mimics, cells, microgravity, cellular, study, examining, interaction, vortical, flows, exposure, significantly, study, examining, interaction, vortical, flows, cells, reveals, microgravity, induces, significant
Abstractive Keywords
study, examining, interaction, vortical, flows, cells, reveals, microgravity, induces, significant
Extractive Keywords
cells, microgravity, cellular, study, examining, interaction, vortical, flows, exposure, significantly
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