Mitigation and use of biofilms in space for the benefit of human space exploration
Metabolism & Nutrition
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synergistic, effects, weightlessness, isoproterenol, radiation, damage, response, cytokine, production, immune
function, cell, study, examining, synergistic, effects, weightlessness, isoproterenol, radiation, space
cell, study, examining, synergistic, effects, weightlessness, isoproterenol, radiation, spaceflight, induced
Study examining synergistic effects of weightlessness, isoproterenol, and radiation on. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Study examining synergistic effects of weightlessness, isoproterenol, and radiation on. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.