Articles
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Gene Expression & Molecular Biology
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Salivary Gland Protein Expression after Bion-M1 and Space Shuttle STS-135 Missions
Salivary Gland Protein Expression after Bion-M1 and Space Shuttle STS-135 Missions
Gene Expression & Molecular Biology
Abstractive Summary
Study examining salivary gland protein expression after bion-m1 and space. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining salivary gland protein expression after bion-m1 and space. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
salivary, gland, protein, expression, after, bion, space, shuttle, missions, genes, expression, after, study, examining, salivary, gland, protein, bion, space, expression, after, changes, long, study, examining, salivary, gland, protein, bion
Abstractive Keywords
expression, after, changes, long, study, examining, salivary, gland, protein, bion
Extractive Keywords
genes, expression, after, study, examining, salivary, gland, protein, bion, space
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