Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
Cardiovascular & Fluid Dynamics
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Study examining secretome profiling reveals acute changes in oxidative stress,. Spaceflight affects neurological function through multiple mechanisms, including cognitive decline, brain structure changes, and increased intracranial pressure. Vestibular adaptation and motor control are temporarily impaired. These findings are critical for understanding astronaut performance and long-term neurological health.
Study examining secretome profiling reveals acute changes in oxidative stress,. Neurological function showed multiple alterations during spaceflight. Cognitive performance declined in attention and spatial processing tasks. Brain structure changes included gray matter volume shifts. Intracranial pressure increased with optic nerve changes. Vestibular system adaptation required 3-7 days. Motor control and coordination were temporarily impaired. Neurotransmitter levels fluctuated significantly.