Simulated micro-, lunar, and Martian gravities on Earth—effects on Escherichia coli growth, phenotype, and sensitivity to antibiotics.
Microbiome & Environmental Microbiology
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lymphatic, burn, injury, associated, mhcii, immune, cell, accumulation, around, vessels
cell, immune, function, study, examining, burn, injury, associated, mhcii, accumulation
cell, immune, study, examining, burn, injury, associated, mhcii, accumulation, around
Study examining burn injury-associated mhcii(+) immune cell accumulation around lymphatic. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Study examining burn injury-associated mhcii(+) immune cell accumulation around lymphatic. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.