Articles
●
Gene Expression & Molecular Biology
●
Spaceflight Activates Autophagy Programs and the Proteasome in Mouse Liver
Spaceflight Activates Autophagy Programs and the Proteasome in Mouse Liver
Gene Expression & Molecular Biology
Abstractive Summary
Study examining is spaceflight-induced immune dysfunction linked to systemic changes. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Extractive Summary
Study examining is spaceflight-induced immune dysfunction linked to systemic changes. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.
394
Keywords
spaceflight, induced, immune, dysfunction, linked, systemic, changes, metabolism, spaceflight, induced, immune, cell, study, examining, dysfunction, linked, systemic, changes, immune, function, cell, study, examining, spaceflight, induced, dysfunction, linked, systemic
Abstractive Keywords
immune, function, cell, study, examining, spaceflight, induced, dysfunction, linked, systemic
Extractive Keywords
spaceflight, induced, immune, cell, study, examining, dysfunction, linked, systemic, changes
Topic Match Articles