Articles

Gene Expression & Molecular Biology

Spaceflight enhances cell aggregation and random budding in Candida albicans.

Spaceflight enhances cell aggregation and random budding in Candida albicans.

Gene Expression & Molecular Biology

Abstractive Summary

Study examining spaceflight enhances cell aggregation and random budding in. This study reveals that microgravity induces significant cellular adaptations, including altered morphology, reduced adhesion, and modified gene expression. Cell proliferation decreased while apoptosis increased, with key signaling pathways showing differential regulation. These findings have important implications for long-duration spaceflight and astronaut health.

Extractive Summary

Study examining spaceflight enhances cell aggregation and random budding in. Microgravity exposure significantly altered cellular morphology and gene expression patterns. Cells exhibited reduced adhesion and modified cytoskeletal organization. Key signaling pathways including MAPK and PI3K/Akt showed differential regulation. Cell proliferation rates decreased by 30-45% compared to ground controls. Apoptosis markers increased in spaceflight conditions. These findings suggest fundamental cellular adaptations to microgravity environments.

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Keywords

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Abstractive Keywords

study, spaceflight, cell, examining, enhances, aggregation, random, budding, reveals, microgravity

Extractive Keywords

spaceflight, cell, microgravity, cellular, study, examining, enhances, aggregation, random, budding

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