Articles
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Metabolism & Nutrition
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Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses.
Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses.
Metabolism & Nutrition
Abstractive Summary
Study examining interplay of space radiation and microgravity in dna. Exposure to cosmic radiation causes substantial DNA damage and oxidative stress, with repair mechanisms partially effective. Cell cycle checkpoints and apoptosis are activated, but long-term cancer risk remains elevated at 3-5% for Mars missions. Effective radiation countermeasures are critical for deep space exploration.
Extractive Summary
Study examining interplay of space radiation and microgravity in dna. Cosmic radiation exposure caused significant DNA damage with increased double-strand breaks. Cellular repair mechanisms were partially effective but overwhelmed at higher doses. Oxidative stress markers were elevated substantially. Cell cycle checkpoints showed prolonged activation. Apoptosis rates increased dose-dependently. Long-term cancer risk estimates ranged from 3-5% for Mars missions.
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Keywords
damage, interplay, space, radiation, microgravity, response, radiation, increased, study, examining, interplay, space, microgravity, cosmic, exposure, caused, radiation, space, effective, study, examining, interplay, microgravity, exposure, cosmic, causes
Abstractive Keywords
radiation, space, effective, study, examining, interplay, microgravity, exposure, cosmic, causes
Extractive Keywords
radiation, increased, study, examining, interplay, space, microgravity, cosmic, exposure, caused
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