The influence of spaceflight on the astronaut salivary microbiome and the search for a microbiome biomarker for viral reactivation
Gene Expression & Molecular Biology
microbiome, influence, spaceflight, astronaut, salivary, search, biomarker, viral, reactivation, spaceflight, cell, study, examining, influence, astronaut, salivary, induced, significant, immune, function, cell, study, examining, influence, spaceflight, astronaut, salivary, space, travel
microbiome, influence, spaceflight, astronaut, salivary, search, biomarker, viral, reactivation
function, cell, study, examining, influence, spaceflight, astronaut, salivary, space, travel
spaceflight, cell, study, examining, influence, astronaut, salivary, induced, significant, immune
Study examining the influence of spaceflight on the astronaut salivary. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Study examining the influence of spaceflight on the astronaut salivary. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.