Articles
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Plant Biology & Bioregenerative Systems
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Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans and Comparison to Spaceflight Experiments.
Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans and Comparison to Spaceflight Experiments.
Plant Biology & Bioregenerative Systems
Abstractive Summary
Study examining effects of liquid cultivation on gene expression and. Spaceflight triggers widespread changes in gene expression affecting stress responses, DNA repair, and mitochondrial function. Epigenetic modifications occur, with some changes persisting long after return. Understanding these molecular adaptations is fundamental to developing effective countermeasures for long-duration missions.
Extractive Summary
Study examining effects of liquid cultivation on gene expression and. Genome-wide expression analysis revealed thousands of differentially expressed genes. Stress response pathways were universally upregulated. DNA repair genes showed increased expression. Mitochondrial genes were downregulated substantially. Epigenetic modifications included altered methylation patterns. Some changes persisted months after return to Earth. Cell cycle regulation genes were significantly affected.
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Keywords
effects, liquid, cultivation, gene, expression, phenotype, elegans, genes, expression, study, examining, effects, liquid, cultivation, gene, genome, wide, gene, expression, changes, long, study, examining, effects, liquid, cultivation, spaceflight
Abstractive Keywords
gene, expression, changes, long, study, examining, effects, liquid, cultivation, spaceflight
Extractive Keywords
genes, expression, study, examining, effects, liquid, cultivation, gene, genome, wide
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