Articles

●

Metabolism & Nutrition

●

Œ±Klotho decreases after reduced weight-bearing from both spaceflight and hindlimb unloading

Metabolism & Nutrition

Abstractive Summary

Study examining knee and hip joint cartilage damage from combined. Exposure to cosmic radiation causes substantial DNA damage and oxidative stress, with repair mechanisms partially effective. Cell cycle checkpoints and apoptosis are activated, but long-term cancer risk remains elevated at 3-5% for Mars missions. Effective radiation countermeasures are critical for deep space exploration.

Extractive Summary

Study examining knee and hip joint cartilage damage from combined. Cosmic radiation exposure caused significant DNA damage with increased double-strand breaks. Cellular repair mechanisms were partially effective but overwhelmed at higher doses. Oxidative stress markers were elevated substantially. Cell cycle checkpoints showed prolonged activation. Apoptosis rates increased dose-dependently. Long-term cancer risk estimates ranged from 3-5% for Mars missions.

560

Keywords

knee, joint, cartilage, damage, from, combined, spaceflight, hazards, dose, radiation, damage, from, increased, study, examining, knee, joint, cartilage, combined, cosmic, damage, radiation, effective, study, examining, knee, joint, cartilage, from, combined

Abstractive Keywords

damage, radiation, effective, study, examining, knee, joint, cartilage, from, combined

Extractive Keywords

damage, from, increased, study, examining, knee, joint, cartilage, combined, cosmic

Topic Match Articles

Characterization of Aspergillus niger Isolated from the International Space Station

Multi-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains

Succession and persistence of microbial communities and antimicrobial resistance genes associated with International Space Station environmental surfaces