A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: Host extracellular to systemic effects of SARS-CoV-2 infection
Cellular & Tissue Engineering
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Study examining a comprehensive sars-cov-2 and covid-19 review, part 2:. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Study examining a comprehensive sars-cov-2 and covid-19 review, part 2:. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.