Articles
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Cellular & Tissue Engineering
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Dose- and Ion-Dependent Effects in the Oxidative Stress Response to Space-Like Radiation Exposure in the Skeletal System
Dose- and Ion-Dependent Effects in the Oxidative Stress Response to Space-Like Radiation Exposure in the Skeletal System
Cellular & Tissue Engineering
Abstractive Summary
Space radiation poses significant health risks to astronauts on deep space missions. This study investigated how different radiation types and doses affect oxidative stress responses. Results demonstrated that high-energy particles cause more severe cellular damage than traditional radiation, emphasizing the need for enhanced radiation protection strategies for Mars missions and beyond.
Extractive Summary
Space radiation exposure causes dose-dependent and ion-specific oxidative stress responses in biological systems. High-LET particles induced more severe oxidative damage compared to low-LET radiation. Antioxidant enzyme activities varied significantly based on radiation type and dose. The study provides crucial data for radiation risk assessment during deep space missions. Understanding these dose-response relationships is essential for developing effective radiation countermeasures.
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Keywords
dose, dependent, effects, oxidative, stress, response, space, like, radiation, exposure, radiation, dose, space, oxidative, exposure, causes, dependent, specific, stress, responses, radiation, space, missions, poses, significant, health, risks, astronauts, deep, study
Abstractive Keywords
radiation, space, missions, poses, significant, health, risks, astronauts, deep, study
Extractive Keywords
radiation, dose, space, oxidative, exposure, causes, dependent, specific, stress, responses
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