Articles
●
Cellular & Tissue Engineering
●
Effects of ex vivo ionizing radiation on collagen structure and whole-bone mechanical properties of mouse vertebrae.
Effects of ex vivo ionizing radiation on collagen structure and whole-bone mechanical properties of mouse vertebrae.
Cellular & Tissue Engineering
Abstractive Summary
Space radiation may affect the structural integrity of biological tissues through damage to collagen, a critical protein in connective tissue. This study examined radiation effects on collagen structure and mechanical properties. Results showed dose-dependent degradation of collagen organization and strength, suggesting potential concerns for tissue health during long-duration spaceflight and the need for protective strategies.
Extractive Summary
Ionizing radiation exposure significantly altered collagen structure and mechanical properties in tissue samples. Radiation-induced damage accumulated with increasing dose, affecting collagen fibril organization. Mechanical testing revealed decreased tensile strength and elasticity in irradiated samples. Structural analysis using microscopy showed disruption of collagen cross-linking patterns. These findings have implications for tissue engineering and radiation protection in space environments.
10
Keywords
effects, vivo, ionizing, radiation, collagen, structure, whole, bone, mechanical, properties, radiation, collagen, mechanical, tissue, samples, ionizing, exposure, significantly, altered, structure, collagen, radiation, tissue, space, affect, structural, integrity, biological, tissues, through
Abstractive Keywords
collagen, radiation, tissue, space, affect, structural, integrity, biological, tissues, through
Extractive Keywords
radiation, collagen, mechanical, tissue, samples, ionizing, exposure, significantly, altered, structure
Topic Match Articles