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Cellular & Tissue Engineering

GeneLab database analyses suggest long-term impact of space radiation on the cardiovascular system by the activation of FYN through reactive oxygen species.

GeneLab database analyses suggest long-term impact of space radiation on the cardiovascular system by the activation of FYN through reactive oxygen species.

Cellular & Tissue Engineering

Abstractive Summary

Study examining genelab database analyses suggest long-term impact of space. Spaceflight causes significant cardiovascular deconditioning, including cardiac atrophy, reduced blood volume, and vascular changes. Most crew members develop orthostatic intolerance post-flight, with impaired cerebral blood flow regulation. Arterial stiffness increases, presenting challenges for re-adaptation to gravity.

Extractive Summary

Study examining genelab database analyses suggest long-term impact of space. Cardiovascular deconditioning was observed with reduced cardiac mass and altered vascular function. Blood volume decreased by 10-15% within first weeks. Orthostatic intolerance developed in 70% of crew post-flight. Carotid artery stiffness increased during flight. Cardiac atrophy affected left ventricular mass. Cerebral blood flow regulation was impaired upon return to gravity.

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Keywords

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Abstractive Keywords

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Extractive Keywords

cardiac, mass, blood, flight, study, examining, genelab, database, analyses, suggest

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