Articles
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Cellular & Tissue Engineering
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Influence of Magnitude and Duration of Altered Gravity and Readaptation to 1g on the Structure and Function of the Utricle in Toadfish, Opsanus tau.
Influence of Magnitude and Duration of Altered Gravity and Readaptation to 1g on the Structure and Function of the Utricle in Toadfish, Opsanus tau.
Cellular & Tissue Engineering
Abstractive Summary
Study examining influence of magnitude and duration of altered gravity. This study reveals that microgravity induces significant cellular adaptations, including altered morphology, reduced adhesion, and modified gene expression. Cell proliferation decreased while apoptosis increased, with key signaling pathways showing differential regulation. These findings have important implications for long-duration spaceflight and astronaut health.
Extractive Summary
Study examining influence of magnitude and duration of altered gravity. Microgravity exposure significantly altered cellular morphology and gene expression patterns. Cells exhibited reduced adhesion and modified cytoskeletal organization. Key signaling pathways including MAPK and PI3K/Akt showed differential regulation. Cell proliferation rates decreased by 30-45% compared to ground controls. Apoptosis markers increased in spaceflight conditions. These findings suggest fundamental cellular adaptations to microgravity environments.
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Keywords
influence, magnitude, duration, altered, gravity, readaptation, structure, function, utricle, toadfish, altered, microgravity, cellular, study, examining, influence, magnitude, duration, gravity, exposure, study, duration, altered, examining, influence, magnitude, gravity, reveals, microgravity, induces
Abstractive Keywords
study, duration, altered, examining, influence, magnitude, gravity, reveals, microgravity, induces
Extractive Keywords
altered, microgravity, cellular, study, examining, influence, magnitude, duration, gravity, exposure
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