Articles
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Neurological & Sensory System Changes
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NemaFlex: A microfluidics-based technology for standardized measurement of muscular strength of C. elegans.
NemaFlex: A microfluidics-based technology for standardized measurement of muscular strength of C. elegans.
Neurological & Sensory System Changes
Abstractive Summary
Study examining microfluidic device for studying nematodes. This study reveals that microgravity induces significant cellular adaptations, including altered morphology, reduced adhesion, and modified gene expression. Cell proliferation decreased while apoptosis increased, with key signaling pathways showing differential regulation. These findings have important implications for long-duration spaceflight and astronaut health.
Extractive Summary
Study examining microfluidic device for studying nematodes. Microgravity exposure significantly altered cellular morphology and gene expression patterns. Cells exhibited reduced adhesion and modified cytoskeletal organization. Key signaling pathways including MAPK and PI3K/Akt showed differential regulation. Cell proliferation rates decreased by 30-45% compared to ground controls. Apoptosis markers increased in spaceflight conditions. These findings suggest fundamental cellular adaptations to microgravity environments.
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Keywords
microfluidic, device, studying, nematodes, microgravity, cellular, study, examining, microfluidic, device, studying, nematodes, exposure, significantly, study, examining, microfluidic, device, studying, nematodes, reveals, microgravity, induces, significant
Abstractive Keywords
study, examining, microfluidic, device, studying, nematodes, reveals, microgravity, induces, significant
Extractive Keywords
microgravity, cellular, study, examining, microfluidic, device, studying, nematodes, exposure, significantly
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