Articles
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Neurological & Sensory System Changes
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Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function
Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function
Neurological & Sensory System Changes
Abstractive Summary
Study examining transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology.. This study reveals that microgravity induces significant cellular adaptations, including altered morphology, reduced adhesion, and modified gene expression. Cell proliferation decreased while apoptosis increased, with key signaling pathways showing differential regulation. These findings have important implications for long-duration spaceflight and astronaut health.
Extractive Summary
Study examining transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology.. Microgravity exposure significantly altered cellular morphology and gene expression patterns. Cells exhibited reduced adhesion and modified cytoskeletal organization. Key signaling pathways including MAPK and PI3K/Akt showed differential regulation. Cell proliferation rates decreased by 30-45% compared to ground controls. Apoptosis markers increased in spaceflight conditions. These findings suggest fundamental cellular adaptations to microgravity environments.
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Keywords
transcriptomics, analysis, reveals, molecular, alterations, underpinning, spaceflight, dermatology, spaceflight, microgravity, cellular, study, examining, transcriptomics, analysis, reveals, molecular, alterations, study, reveals, spaceflight, examining, transcriptomics, analysis, molecular, alterations, underpinning, dermatology
Abstractive Keywords
study, reveals, spaceflight, examining, transcriptomics, analysis, molecular, alterations, underpinning, dermatology
Extractive Keywords
spaceflight, microgravity, cellular, study, examining, transcriptomics, analysis, reveals, molecular, alterations
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