Articles
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Cellular & Tissue Engineering
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Proteomic and phosphoproteomic characterization of cardiovascular tissues after long term exposure to simulated space radiation
Proteomic and phosphoproteomic characterization of cardiovascular tissues after long term exposure to simulated space radiation
Cellular & Tissue Engineering
Abstractive Summary
Study examining proteomic and phosphoproteomic characterization of cardiovascular tissues after. Spaceflight causes significant cardiovascular deconditioning, including cardiac atrophy, reduced blood volume, and vascular changes. Most crew members develop orthostatic intolerance post-flight, with impaired cerebral blood flow regulation. Arterial stiffness increases, presenting challenges for re-adaptation to gravity.
Extractive Summary
Study examining proteomic and phosphoproteomic characterization of cardiovascular tissues after. Cardiovascular deconditioning was observed with reduced cardiac mass and altered vascular function. Blood volume decreased by 10-15% within first weeks. Orthostatic intolerance developed in 70% of crew post-flight. Carotid artery stiffness increased during flight. Cardiac atrophy affected left ventricular mass. Cerebral blood flow regulation was impaired upon return to gravity.
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Keywords
proteomic, phosphoproteomic, characterization, cardiovascular, tissues, after, long, term, exposure, simulated, cardiovascular, cardiac, mass, blood, flight, study, examining, proteomic, phosphoproteomic, characterization, cardiovascular, blood, study, examining, proteomic, phosphoproteomic, characterization, tissues, after, spaceflight
Abstractive Keywords
cardiovascular, blood, study, examining, proteomic, phosphoproteomic, characterization, tissues, after, spaceflight
Extractive Keywords
cardiovascular, cardiac, mass, blood, flight, study, examining, proteomic, phosphoproteomic, characterization
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