Rad-Bio-App: A discovery environment for biologists to explore spaceflight-related radiation exposures
Immune System Function & Infection
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Study examining rad-bio-app: a discovery environment for biologists to explore. Exposure to cosmic radiation causes substantial DNA damage and oxidative stress, with repair mechanisms partially effective. Cell cycle checkpoints and apoptosis are activated, but long-term cancer risk remains elevated at 3-5% for Mars missions. Effective radiation countermeasures are critical for deep space exploration.
Study examining rad-bio-app: a discovery environment for biologists to explore. Cosmic radiation exposure caused significant DNA damage with increased double-strand breaks. Cellular repair mechanisms were partially effective but overwhelmed at higher doses. Oxidative stress markers were elevated substantially. Cell cycle checkpoints showed prolonged activation. Apoptosis rates increased dose-dependently. Long-term cancer risk estimates ranged from 3-5% for Mars missions.