Articles
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Neurological & Sensory System Changes
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Simulated Microgravity Promotes Horizontal Gene Transfer of Antimicrobial Resistance Genes between Bacterial Genera in the Absence of Antibiotic Selective Pressure
Simulated Microgravity Promotes Horizontal Gene Transfer of Antimicrobial Resistance Genes between Bacterial Genera in the Absence of Antibiotic Selective Pressure
Neurological & Sensory System Changes
Abstractive Summary
Study examining bone marrow adipose tissue is not required for. Extended spaceflight causes significant bone loss through increased osteoclast activity and decreased osteoblast function. Calcium metabolism is disrupted, with elevated resorption markers. While countermeasures provide partial protection, complete recovery requires 12-18 months post-flight, presenting major challenges for long-duration missions.
Extractive Summary
Study examining bone marrow adipose tissue is not required for. Bone mineral density decreased significantly during extended spaceflight missions. Osteoclast activity increased while osteoblast function declined. Calcium metabolism was disrupted with elevated urinary calcium excretion. Bone resorption markers TRAP and CTX-1 were significantly elevated. Mechanical loading countermeasures showed partial effectiveness. Recovery of bone density post-flight required 12-18 months on average.
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Keywords
bone, marrow, adipose, tissue, required, reconstitution, immune, system, following, irradiation, bone, required, density, significantly, calcium, elevated, study, examining, marrow, adipose, bone, study, examining, marrow, adipose, tissue, required, extended, spaceflight, causes
Abstractive Keywords
bone, study, examining, marrow, adipose, tissue, required, extended, spaceflight, causes
Extractive Keywords
bone, required, density, significantly, calcium, elevated, study, examining, marrow, adipose
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