Articles
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Immune System Function & Infection
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Spaceflight and simulated microgravity conditions increase virulence of Serratia marcescens in the Drosophila melanogaster infection model.
Spaceflight and simulated microgravity conditions increase virulence of Serratia marcescens in the Drosophila melanogaster infection model.
Immune System Function & Infection
Abstractive Summary
Study examining spaceflight and simulated microgravity conditions increase virulence of. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Extractive Summary
Study examining spaceflight and simulated microgravity conditions increase virulence of. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.
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Keywords
spaceflight, simulated, microgravity, conditions, increase, virulence, serratia, marcescens, drosophila, melanogaster, spaceflight, cell, study, examining, simulated, microgravity, conditions, increase, virulence, induced, function, cell, study, examining, spaceflight, simulated, microgravity, conditions, increase, virulence
Abstractive Keywords
function, cell, study, examining, spaceflight, simulated, microgravity, conditions, increase, virulence
Extractive Keywords
spaceflight, cell, study, examining, simulated, microgravity, conditions, increase, virulence, induced
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