Articles
●
Cellular & Tissue Engineering
●
Spaceflight-associated vascular remodeling and gene expression in mouse calvaria.
Spaceflight-associated vascular remodeling and gene expression in mouse calvaria.
Cellular & Tissue Engineering
Abstractive Summary
Study examining spaceflight-associated vascular remodeling and gene expression in mouse. Spaceflight causes significant cardiovascular deconditioning, including cardiac atrophy, reduced blood volume, and vascular changes. Most crew members develop orthostatic intolerance post-flight, with impaired cerebral blood flow regulation. Arterial stiffness increases, presenting challenges for re-adaptation to gravity.
Extractive Summary
Study examining spaceflight-associated vascular remodeling and gene expression in mouse. Cardiovascular deconditioning was observed with reduced cardiac mass and altered vascular function. Blood volume decreased by 10-15% within first weeks. Orthostatic intolerance developed in 70% of crew post-flight. Carotid artery stiffness increased during flight. Cardiac atrophy affected left ventricular mass. Cerebral blood flow regulation was impaired upon return to gravity.
214
Keywords
spaceflight, associated, vascular, remodeling, gene, expression, mouse, calvaria, vascular, cardiac, mass, blood, flight, study, examining, spaceflight, associated, remodeling, spaceflight, vascular, blood, study, examining, associated, remodeling, gene, expression, mouse
Abstractive Keywords
spaceflight, vascular, blood, study, examining, associated, remodeling, gene, expression, mouse
Extractive Keywords
vascular, cardiac, mass, blood, flight, study, examining, spaceflight, associated, remodeling
Topic Match Articles