Articles
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Cellular & Tissue Engineering
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Toll mediated infection response is altered by gravity and spaceflight in Drosophila
Toll mediated infection response is altered by gravity and spaceflight in Drosophila
Cellular & Tissue Engineering
Abstractive Summary
Study examining toll mediated infection response is altered by gravity. Space travel significantly compromises immune function through impaired T-cell activity, reduced NK cell function, and inflammatory cytokine dysregulation. Latent viruses frequently reactivate, and wound healing is delayed. These findings raise concerns about infection risk and vaccine effectiveness during long missions.
Extractive Summary
Study examining toll mediated infection response is altered by gravity. Spaceflight induced significant immune system dysregulation. T-cell function was impaired with reduced proliferation capacity. Natural killer cell activity decreased substantially. Cytokine profiles shifted toward pro-inflammatory states. Latent viral reactivation occurred in 60% of crew members. Wound healing processes were delayed. Vaccine efficacy may be compromised in space environments.
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Keywords
toll, mediated, infection, response, altered, gravity, spaceflight, drosophila, cell, study, examining, toll, mediated, infection, response, altered, gravity, spaceflight, infection, function, cell, study, examining, toll, mediated, response, altered, gravity
Abstractive Keywords
infection, function, cell, study, examining, toll, mediated, response, altered, gravity
Extractive Keywords
cell, study, examining, toll, mediated, infection, response, altered, gravity, spaceflight
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