A New Era for Space Life Science: International Standards for Space Omics Processing
Radiation Biology & DNA Damage
space, life, science, international, standards, omics, processing, bone, density, loss, increased, calcium, paper, space, life, science, international, bone, paper, space, life, science, international, standards, study, documented, significant
space, life, science, international, standards, omics, processing
bone, paper, space, life, science, international, standards, study, documented, significant
bone, density, loss, increased, calcium, paper, space, life, science, international
The study documented significant bone density loss during spaceflight due to altered bone cell activity and calcium metabolism. While exercise countermeasures helped, complete prevention was not achieved, and recovery took months after return, highlighting the need for improved interventions.
Bone density loss occurred at a rate of 1-2% per month during spaceflight. Osteoclast activity increased while osteoblast function decreased. Calcium metabolism was disrupted with increased urinary calcium excretion. Exercise countermeasures attenuated but did not prevent bone loss. Recovery of bone density post-flight required 6-12 months.