Effect of spaceflight on Pseudomonas aeruginosa final cell density is modulated by nutrient and oxygen availability.
Radiation Biology & DNA Damage
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This study assessed radiation risks for deep space missions, documenting DNA damage and increased cancer risk from cosmic ray exposure. The findings emphasize the critical need for effective shielding strategies and potential pharmacological countermeasures for Mars missions.
Radiation exposure from cosmic rays and solar particle events poses significant health risks. DNA double-strand breaks increased with radiation dose. Oxidative stress markers were elevated. Long-term cancer risk estimates ranged from 3-5% for Mars mission durations. Shielding effectiveness varied by material composition and thickness.