Spaceflight promotes biofilm formation by Pseudomonas aeruginosa.
Radiation Biology & DNA Damage
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Research revealed substantial changes in gut microbiome composition during spaceflight, with decreased diversity and increased pathogens. These shifts correlated with immune dysfunction, suggesting that microbiome-targeted interventions like probiotics may help maintain astronaut health.
Gut microbiome composition shifted significantly during spaceflight. Microbial diversity decreased with reduced beneficial species. Opportunistic pathogens increased in relative abundance. These microbiome changes correlated with immune function alterations. Probiotic supplementation showed potential as a countermeasure.