Metabolomic profiling of the secretome from human neural stem cells flown into space.
Radiation Biology & DNA Damage
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Study examining metabolomic profiling of the secretome from human neural. Spaceflight affects neurological function through multiple mechanisms, including cognitive decline, brain structure changes, and increased intracranial pressure. Vestibular adaptation and motor control are temporarily impaired. These findings are critical for understanding astronaut performance and long-term neurological health.
Study examining metabolomic profiling of the secretome from human neural. Neurological function showed multiple alterations during spaceflight. Cognitive performance declined in attention and spatial processing tasks. Brain structure changes included gray matter volume shifts. Intracranial pressure increased with optic nerve changes. Vestibular system adaptation required 3-7 days. Motor control and coordination were temporarily impaired. Neurotransmitter levels fluctuated significantly.